The assailants, masked and heavily armed, approached the victim in his red Toyota Corolla, quickly firing warning shots to disperse bystanders before seizing sacks of cash from the vehicle.
The intense scene, shows vendors and shoppers scrambling for safety as shots echoed through the area.
The robbers, who swiftly loaded the cash into their getaway vehicle, were gone within minutes, leaving the market shaken.
Eyewitnesses described the attackers as highly organized, employing tactics that seemed well-rehearsed.
The Ghana Police Service has since launched a targeted manhunt to track down the perpetrators.
Authorities have appealed to anyone with further information to come forward, as they work to enhance security and prevent future incidents.