On Tuesday evening, dozens of stores at Ritz Junction in the Adentan municipality were demolished.
The inferno's origin was unknown at the time, but a business owner by the name of Solomon informed Media General's Richard Bright Addo that a quarrel between two of the residents was what started it.
According to witnesses, it began at 10:30 p.m.
Staff from the Ghana National Fire Service (GNFS) were on the site putting out the fire as of 1:00 am on Wednesday.
Five tenders were brought into the battle, and it has now been brought under control.
To safeguard people and property, there were several police officers there.
According to the Service's Public Relations Officer (PRO), there were no injuries.
According to Alex Nartey, our correspondent, even though the origin of the fire cannot be immediately known, he will not rule out arson.